❤ ❤ A new version of Model Organism Phenotype Enrichment Analysis tool is now available. ❤ ❤
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MamPhEA
DroPhEA
SOURCE OF GENE LISTS:
Organism:
Mus musculus (mouse)
Rattus norvegicus (rat)
Homo sapiens (human)
Pan troglodytes (chimpanzee)
Bos taurus (cow)
Canis familiaris (dog)
Cavia porcellus (guinea pig)
Choloepus hoffmanni (sloth)
Dasypus novemcinctus (armadillo)
Dipodomys ordii (kangaroo rat)
Echinops telfairi (lesser hedgehog tenrec)
Erinaceus europaeus (hedgehog)
Equus caballus (horse)
Felis catus (cat)
Gorilla gorilla (gorilla)
Loxodonta africana (elephant)
Macaca mulatta (macaque)
Macropus eugenii (wallaby)
Microcebus murinus (mouse lemur)
Monodelphis domestica (opossum)
Myotis lucifugus (microbat)
Ochotona princeps (pika)
Ornithorhynchus anatinus (platypus)
Oryctolagus cuniculus (rabbit)
Otolemur garnettii (bushbaby)
Pongo pygmaeus (orangutan)
Procavia capensis (hyrax)
Pteropus vampyrus (megabat)
Sorex araneus (shrew)
Sus scrofa (pig)
Tarsius syrichta (tarsier)
Tupaia belangeri (tree shrew)
Tursiops truncatus (dolphin)
Vicugna pacos (alpaca)
Aedes aegypti (yellow fever mosquito)
Anopheles gambiae (african malaria mosquito)
Apis mellifera (honey bee)
Acyrthosiphon pisum (pea Aphid)
Bombyx mori (silk moth)
Culex pipiens (common house mosquito)
Drosophila ananassae (fruit fly)
Drosophila grimshawi (fruit fly)
Drosophila melanogaster (fruit fly)
Drosophila mojavensis (fruit fly)
Drosophila pseudoobscura (fruit fly)
Drosophila virilis (fruit fly)
Drosophila willistoni (fruit fly)
Ixodes scapularis (tick)
Nasonia vitripennis (wasp)
Pediculus humanus (human louse)
Tribolium castaneum (red flour beetle)
GENE SETS TO BE ANALYZED:
Name of Gene Set 1:
Name of Gene Set 2:
Rest of genome
example 1.1
,
example 1.2
,
example 2
example 1
example 2
Example 1.1:
Species: Fruit fly (
Drosophila melanogaster
)
Data set 1: One-to-one human orthologous fly gene
Data set 2: Background
Example 1.2:
Species: Fruit fly (
Drosophila melanogaster
)
Data set 1: No human orthologous fly gene
Data set 2: Background
Example 2:
Species: African malaria mosquito (
Anopheles gambiae
)
Data set 1: Top 20% highly expressed gene after a Blood-meal
Data set 2: Bottom 80% lowly expressed gene after a Blood-meal
Example 1:
Species: Human (
Homo sapiens
)
Data set 1: Liver (top 20%)
Data set 2: Testes (top 20%)
Example 2:
Species: Mouse (
Mus musculus
)
Data set 1: Brain (top 20%)
Data set 2: Brain (bottom 20%)
Mus musculus
uses
Ensembl
database ID
e.g.ENSMUSG00000014791,ENSMUSG00000024335,ENSMUSG00000042460
ALTERNATIVE HYPOTHESIS:
Fisher's exact test:
differentially enriched
set 1 enriched
set 1 depleted
MUTANT PHENOTYPES:
Phenotyped Organism:
Mus musculus (mouse)
Drosophila melanogaster (fruit fly)
Remove phenotypic entries caused by gain-of-function mutation(s)
Use loss-of-function phenotypes only
One-to-one orthologs only
Enrichment Analysis on MGI pre-defined Phenotypes
Enrichment Analysis on User-defined Phenotypes
MGI pre-defined Phenotypes
at Level
2
3
4
5
6
7
8
9
10
11
12
13
14
to Level
2
3
4
5
6
7
8
9
10
11
12
13
14
Show full phenotypic classes
FlyBase pre-defined Phenotypes
at Level
2
3
4
5
6
7
8
9
10
11
12
13
14
to Level
2
3
4
5
6
7
8
9
10
11
12
13
14
Show full phenotypic classes
Manually Input Phenotypes
Select Terms from FBcv Ontology
Select Terms from FBbt Ontology
Select Terms from Mammalian Phenotype Ontology
Keyword search
e.g. FBcv:0000351,FBbt:00005397 (lateral | embryonic epidermis)
e.g. MP:0002080,MP:0002160 (prenatal lethality, abnormal reproductive system morphology)
Search Phenotype:
Selected Phenotype:
Name:
User-defined Phenotype
SUBMIT:
Division of Biostatistics and Bioinformatics
Institute of Population Health Sciences
National Health Research Institutes, Taiwan, ROC
All Rights Reserved
Last update 01/28/2016 (
see more info
)
